the Amen Break
The most famous drum beat in the world, in a duration of 6 seconds. This drum beat alone has been sampled about 3,000 times in many songs of different genres, including Hip Hop, Jungle, Drum & Bass, and others. It was sampled from a B-Side track called "Amen, Brother" by The Winston's from their 1969 album, "Color Him Father". Barely noticed at the time until the sampler was introduced, it became widely known and inspired by many music artists of today.
Example:
A few example songs that use the Amen Break sample:
N.W.A - Straight Outta Compton
μ-Ziq - Carpet Muncher
Michel Van Den Bos - Foregone Destruction (from the Facing Worlds CTF map in Unreal Tournament '99)
Salt-N-Pepa - I Desire
Rob Base & DJ E-Z Rock - Keep It Going Now
Mantronix - The King of Beats
A few example songs that use the Amen Break sample:
N.W.A - Straight Outta Compton
μ-Ziq - Carpet Muncher
Michel Van Den Bos - Foregone Destruction (from the Facing Worlds CTF map in Unreal Tournament '99)
Salt-N-Pepa - I Desire
Rob Base & DJ E-Z Rock - Keep It Going Now
Mantronix - The King of Beats