strained

To go ham, to push your body to the limits with drugs and alcohol for hedonistic purposes.



Strain
A strain is a genetic variant or subtype of a microorganism (e.g. virus or bacterium or fungus). For example, a "flu strain" is a certain biological form of the influenza or "flu" virus.
Example:
H1N1 is a common strain of influenza


straining
when you try to expel a turd from your large colon by bearing down and pushing like a pregnant woman.
Example:
Doctor: If you keep straining while you are pinching a loaf, your colon will eventually exit your sphincter, and you will get a nasty hemmorhoid.


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